St. Louis got their first win of the series over the Milwaukee Brewers, as the Cardinals used two Yadier Molina home runs to win 3-2 on Saturday.
Sunday's game at Miller Park will determine if the Cardinals split the series or if the Brewers can take three of four from their NL Central rivals.
Milwaukee's offense again struggled, getting only three hits against Cardinals starter Miles Mikolas in the loss.
The Brewers still own the best record in the NL and lead the division by two games over the Cubs, who have lost three in a row.
Video 2: Fox Sports Wisconsin
Videos 1 and 3: MLB