Giannis Antetokounmpo had 27 points and 18 rebounds, Malcolm Brogdon scored 23, and Brook Lopez added 20, but the Bucks lost in overtime to the Clippers 128-126 on Saturday afternoon in Los Angeles.
Eric Bledsoe, who finished with 15 points, hit a three-point shot to send the game to overtime.
Montrezl Harrell led the Clippers in scoring with 26. Patrick Beverley had 21 and Tobias Harris notched 20 points.
The Bucks are now 1-2 on their four-game road trip out West. They'll play the Denver Nuggets Sunday night before returning home for six games beginning on Wednesday.
Videos 1 and 2: Fox Sports Wisconsin
Video 3: NBA